We are families, like you who have been devastated by the effects of Li-Fraumeni Syndrome (LFS), a hereditary genetic cancer predisposition syndrome. Our hopes are to educate, raise awareness, and find better screening programs and treatments for LFS. By forming relationships with and supporting the variety of researchers and medical staff who can help achieve this, we wish to help provide a better understanding of a complex syndrome to those who need it. We welcome communication with all professionals, researchers, scientists, doctors, patients, and families in the hopes that the bridges formed by these communities will lead to an end of the devastating effects of Li-Fraumeni and other Li-Fraumeni-like syndromes.
In November 2010, with the support of the United States’ National Institute of Health (NIH) and the world’s medical leaders of the Li-Fraumeni Syndrome, we all met in Washington D.C. at the first Li-Fraumeni Syndrome Conference. One month later, in December 2010, we officially formed the LFS Association and selected our inaugural Board of Directors.
Frederick Li & Joseph Fraumeni, 1991
(Photo credit: Division of Cancer Epidemiology and Genetics, National Cancer Institute.)
Learn More About Drs. Frederick Li and Joseph Fraumeni
- National Cancer Institute’s Symposium Celebrating 50 Years of Dr. Joseph Fraumeni’s Visionary Leadership (May 2014). See the agenda and video presentations for each speaker, to include the closing remarks on Dr. Fraumeni’s incredible accomplishments.
- Joseph Fraumeni: A 50-Year Legacy of Cancer Research
- “Li-Fraumeni Syndrome: Discovery and Future Challenges” with Dr. David Schottenfeld and Dr. Louise Strong
- “Li-Fraumeni Syndrome: TP53 and Beyond” with Dr. David Malkin
- Dr. Joseph Fraumeni receives the Lifetime Achievement Award by Duke Medical Alumni Association – see the video (October 2014)
- Dr. Frederick Pei Li awarded as Fellow by the American Association of Cancer Research (2014)
- Dr. Joseph Fraumeni awarded as Fellow by the American Association of Cancer Research (2013)
- A Conversation with Joseph F. Fraumeni, Jr. with Dr. Robert N. Hoover, then director of DCEG (November 2013)
- Measuring the Impact of Publications by Dr. Joseph Fraumeni (2012)
- Li-Fraumeni Syndrome: Report of a Clinical Research Workshop and Creation of a Research Consortium (published 2012)
- Celebration of the Career of Frederick P. Li (2008) Remarks by Dr. Fraumeni at Dr. Li’s retirement: “It is a pleasure to pay tribute…
- Frederick Pei Li – Wikipedia bio
- Dr. Joseph Fraumeni – Wikipedia bio
- Charles S. Mott Prize awarded by the General Motors Cancer Research Foundation for the work of Drs. Li and Fraumeni (1995)
- How a Hereditary Multicancer Syndrome Was Discovered (adapted from 1995)
“In the 1960s, Joseph F. Fraumeni, Jr., M.D., and Dr. Robert W. Miller, in what was then the Epidemiology Branch of NCI, began an exploration into the epidemiological patterns of childhood and familial cancer about which little was known…” [Read More] - “Dr. Frederick P. Li, 75; helped prove genetic cancer link” Boston Globe Obituary (June 17, 2015)
- New York Times tribute article to Dr. Frederick Li (June 21, 2015)
- NCI’s Division of Cancer Epidemiology and Genetics published tribute to Dr. Frederick P. Li in 2015 Linkage newsletter
- National Institutes of Health’s NIH Record published tribute to Dr. Li, Li Mourned – Pioneer in Genetic Causes of Cancer
- The History of a Name: The American Society for Preventive Oncology Renames Its Highest Honor The Joseph F. Fraumeni, Jr., Distinguished Achievement Award
At the 4th LFSA International Symposium in Toronto, LFSA presented our inaugural Global Pioneer Award for the groundbreaking work of both Drs. Fred Li and Joseph Fraumeni during a reception at the Hockey Hall of Fame. Watch Dr. Fraumeni’s remarks regarding the early collaborative efforts in their recognition of what was later referred to as Li-Fraumeni syndrome. Note the warmth and respect he offers for not only the relationships developed early in his career, but the admiration he has towards those who continue the pursuit to improve the lives of those with LFS.
Uncovering the Causes of Cancer in the Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute: Watch DCEG Director Dr. Stephen Chanock discuss the visionary work of Drs. Joseph Fraumeni, Robert Hoover, and Margaret Tucker as the first generation of researchers at NCI to focus on the etiology of cancer and the environmental, lifestyle, and genetic influences on cancer. Also featured is Dr. Maria Achatz, the principal investigator of the LFS study at NCI, discussing the early discovery of LFS and the significance of LFS research in carcinogenesis, in general. (October 2017)
The Li-Fraumeni Exploration (LiFE) Research Consortium is composed of dedicated physicians and scientists from around the world. They share a goal of helping to improve the lives of those living with LFS and are advancing our knowledge of this condition through collaborative research.
Learn More About the Next Generation of LFS Researchers
Dr. Judy Garber
- Dana-Farber Cancer Institute (DFCI) Profile
- American Association for Cancer Research’s Biography
- Judy Garber, MD, MPH, Elected to Institute of Medicine
- LFS Association Medical Advisory Board Member
- Li-Fraumeni Syndrome: Report of a Clinical Research Workshop and Creation of a Research Consortium
Dr. David Malkin
- The Hospital for Sick Children’s Biography
- LFS Association International Chapter Chair – Canada
- LFS Association Medical Advisory Board Member
- 2014 Li-Fraumeni syndrome: TP53 and Beyond
Dr. Louise Strong
- American Association of Cancer Research Biography
- LFS Association Medical Advisory Board Member
- 2014 Li-Fraumeni Syndrome: Discovery and Future Challenges
Dr. Joshua Schiffman
- Huntsman Cancer Institute’s Biography
- The Schiffman Lab
- LFS Association Medical Advisory Board Member
Dr. Sharon Savage
- National Cancer Institute’s Division of Cancer Epidemiology and Genetics Biography
- LFS Association Medical Advisory Board Member
Dr Maria Isabel Waddington Achatz, MD
- Sue Armstrong’s “Brazil’s Cancer Curse” (published September 15, 2015).
- LFS Association International Chapter Chair – Latin America
- LFS Association Scientific Advisory Board Member
Dr. Christian Kratz, MD
- Medizinische Hochschule Hannover
- LFS Association International Chapter Chair – Germany
- LFS Association Medical Advisory Board Member
Dr. Kim E. Nichols, MD
- St. Jude’s Children’s Research Hospital – Division of Cancer Predisposition
Dr. Phuong Mai, MD
- LFS Association Medical Advisory Board
Dr. Payal Kincha, MD
Dr. Gareth Evans, MD
Dr. Jeffrey Weitzel, MD
It is with heartfelt appreciation that we acknowledge Sabre Digital Marketing for their continued support with our website, which is our first ever communication tool linking our worldwide LFS community together. Without Sabre Digital Marketing, none of this would have been possible – Thank you!
