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Clustering of TP53 variants into functional classes correlates with cancer risk and identifies different phenotypes of Li-Fraumeni syndrome

High resolution clustering of TP53 variants into functional classes  correlates with cancer risk among germline variant  carriers and identifies different phenotypes of the Li-Fraumeni Syndrome. Emilie Montellier, PhD (1), Nathanaël Lemonnier, PhD (1), Judith Penkert, MD (2), Claire Freycon, MD (1,3,4), Sandrine Blanchet, MSc (1), Amina Amadou, PhD (1,5), Florent Chuffart, PhD (1), Nicholas Fischer,

Li-Fraumeni Syndrome Association Lauds Advancements in Classifying Hereditary Cancer Risks

HOLLISTON, MA -- The Li-Fraumeni Syndrome Association (LFSA), dedicated to furthering research and worldwide awareness of the inherited cancer predisposition disorder, celebrates new findings published in the renowned JAMA Oncology journal with implications to better predict cancer risk. First presented at LFSA's 5th International Symposium last year, the concept of analyzing tumor patterns and

By |2024-07-11T15:16:55-04:00October 28th, 2021|LFS News, Press Release|0 Comments
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