Devoted to a world without inherited cancer

Monthly Archives: March 2025

Seeking Participants for the INFORM Research Study

Dana-Farber is leading an IRB-approved study that will screen for many of the deadliest cancers with a first-of-its-kind blood test. This test will predict the most likely origin of the cancer signal to help guide the next steps for diagnosis. Note that this will not detect all cancers, and false negatives and false positives

By |2025-03-17T12:36:03-04:00March 17th, 2025|LFS News, Study|0 Comments

Update on Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Just published by American Association for Cancer Research (AACR) is the updated version of the “Toronto Protocol,” the widely recognized screening recommendations for Li-Fraumeni syndrome patients, worldwide.  Lead by Dr. David Malkin (LFSA Medical & Scientific Board Member and Co-chair of LFSA – Canada), this new perspective provides an up-to-date clinical overview of LFS

Li-Fraumeni syndrome: predicting cancer risk more precisely

The two MHH researchers Lucas John Müntnich and Professor Christian Kratz refer to the cluster analysis of the study, according to which cancer-free survival depends on the classification of the underlying variant. Copyright: Karin Kaiser/MHH. (With permission.) A new form of cluster analysis enables the development of personalized cancer screening tests.  As presented

Radiotherapy results in decreased time to second cancer in children with Li Fraumeni syndrome

UK researchers conducted a retrospective case-series study of four children diagnosed with solid cancers at age 16 or younger, aiming to assess the time to and survival following a second cancer diagnosis. In those who received radiotherapy for the initial cancer, the median time to a second primary cancer diagnosis was 13.3 years, with a

Go to Top